i was infected by medbot.dc trojan and nod32 always detected the virus and blocked its access to quarantine but never deleted the folder that the virus created (c:\win32\..)
with many suspicious programs and files inside.it never fixed my registry either and kept always detecting the virus from time to time even after it moves the detected files to quarantine . IT JUST NEVER KILLED THE MAIN FILE THAT REPRODUCES THE VIRUS.

well i did an Online Virus Scan with Bitdefender site (http://www.bitdefender.com/) and guess what it detected the threat , cleaned my registry , deleted the folder !
so the result : is one zero for Bitdefender Vs Nod32.( though the bitdefender firewall is so damn complicated and tough it really a forteress that it blocks my own net surfing hehe, i recommend just the scanner and a windows firewall would be lovely)

Ps: its a great idea to have a 1 : A system setup antivirus like Nod32 plus 2 periodical online scan with bitdefender or trendmicro online scanner . u will forget about those antispyware removing programs